5-Fluorouracil is a chemotherapy drug that was patented in 1956. It is used to treat different cancers including colon, breast, skin, stomach, oesophageal (gullet), and pancreatic cancer. It may also be used to treat other cancers.
The drug is usually given by injection into a vein. Topical (on the skin) forms are available too. Basal cell carcinoma and skin warts are some of the indications for the creme.
5-Fluorouracil is classified as an “antimetabolite” and blocks certain enzymes of the DNA. As a result, tumor growth is slowed down.
Folinic acid, also known as leucovorin, is used in combination with 5-fluorouracil to enhance its effect. When given in combination the side effects of 5-Fluorouracil may be more severe.
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Common side effects are:
- dry and itchy skin, skin darkening
- Nausea, vomiting, and loss of appetite
- Mouth sores
- Hair loss
- Low blood counts
Drug interactions may increase your risk of serious side effects. Inform your doctor about all the products you use. It is known that certain antibiotics like metronidazole and blood thinner like warfarin are interacting with 5-Fluorouracil.
How to increase efficacy of 5-Fluorouracil
There are different types of chemotherapy enhancement. Some natural substances can reduce the side effects, some others have similar effects and therefore acting synergistically. The goal of this article is to show that natural substances can be used to improve the chemotherapy outcome. Of course, any treatment should be observed by an experienced physician. It is essential to know the right moment of application, the exact dosage and to have the right formulation.
For my therapies, I only use certified natural products which are mainly applied intravenously into the bloodstream. By doing this, we ensure to have the highest concentration inside and around the tumor cells.